Compound SM-88 from Tyme Technologies (shown as blue hexagons) is a dysfunctional form of tyrosine that disrupts the metabolism of tumor cells, leaving them vulnerable to immune response and ...
It is eliminated by metabolism through the CYP3A4 pathway and excreted through feces. Therefore, if patients are on a potent CYP3A4 inducer such as phenytoin or rifampin, the daily dose of ...
“This gene-to-molecule research is crucial for discovery in Alzheimer’s disease. It offers fresh perspectives on how genetic risk factors, such as APOE, influence metabolism and perhaps disease ...