这篇综述通过系统分析发现，VEGF-A 水平与 COVID-19 严重程度相关，或可作预后指标。 一、研究背景 新型冠状病毒（SARS-CoV-2）引发的 2019 冠状病毒病（COVID-19）自 2019 年爆发以来，迅速演变成全球性健康危机，给人类生命和社会经济带来了沉重打击。该病毒主要 ...

The ability of tumours to induce new blood-vessel formation has been a major focus of cancer research over the past few decades, and vascular endothelial growth factor (VEGF) is now known to be ...

Two independent studies show that ephrin-B2 controls the internalization and signaling of two types of vascular endothelial growth factor (VEGF) receptors—thereby regulating VEGF-induced ...

4D Molecular Therapeutics is undervalued, with its lead candidate 4D-150 showing potential to disrupt the anti-VEGF treatment paradigm for retinal diseases. The company has a strong cash position ...

In September 15 Journal of Clinical Investigation, Hairong Peng and colleagues at the University of Pittsburgh, Pennsylvania, US, show that simultaneous expression of bone morphogenetic protein-4 (BMP ...

Growth factors under investigation include vascular endothelial growth factor (VEGF), and epidermal growth factor (EGF) and its receptor (EGFR). These growth factors are integral to the cancer ...

AE-941 (shark cartilage) targets several steps in tumor angiogenesis, including the blockade of VEGF. However, its primary mechanism is inhibition of matrix metalloproteases (MMPs). MMPs ...

4D-150 is designed to offer sustained delivery of anti-VEGF treatment, potentially alleviating the need for frequent eye injections currently required by patients. The trial aims to demonstrate ...