Did you know that you have a second genome? Small cellular organelles called mitochondria contain their own circular DNA. What happens to your cells when this DNA mutates? Similar to the nuclear ...

The malfunctioning mitochondria seem to poison the immune cells, explains Yosuke Togashi, a pulmonary physician and ...

Mitochondria possess two dynamic membranes that envelop a multi-copy genome essential for aerobic energy metabolism. Metazoan mitochondrial DNA is one of the most constrained and simplified genomes ...

Typically, humans inherit mitochondria and mitochondrial DNA from their mothers only. But using sequencing data from the mitochondrial genomes of members from three unrelated families, researchers ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

However, how mitochondrial DNA (mtDNA) contributes to cancer has been unclear. Scientists at St. Jude Children's Research Hospital studied varying levels of mutated mtDNA to see their effect on ...

Normal metabolic activity produces reactive oxygen species (ROS) that, if not eliminated, can damage cellular components. As a result, ROS from overactive mitochondria are frequently cited as a source ...

Despite being small in size, mitochondria is widely known as the ‘powerhouses’ of the cell, responsible for generating energy ...

The office argues nuclear DNA science is "generally accepted" within the scientific community and "based upon technology that ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death.