Understanding the molecular cross-talk that occurs within the microenvironment between tumor cells and the ECM/other stromal cells may point to opportunities for cotargeting of the tumor and ...

Identifying and understanding pathways of tumor–stroma cross-talk are likely to lead to the development of novel prognostic biomarkers for metastasis and strategies to prevent metastasis at its ...

But many solid tumours in humans have an abundance of stroma, the matrix where tumour-feeding vessels exist. “Clinical cancers — especially pancreatic cancer, stomach cancer and glioblastoma ...

What are germ cell and sex cord stromal cells? Germ cells and sex cord stromal cells form when a fetus (baby) is developing. A fetus is made from a sperm cell and an egg cell. Germ cell tumors (GCTs) ...

Pseudoangiomatous stromal hyperplasia is a rare condition that may be mistaken for breast cancer, but researchers haven’t found a connection between the two conditions. Pseudoangiomatous stromal ...

New research reveals that ER+ breast cancer cells acquire aggressive characteristics through direct contact with bone marrow ...