What was puzzling was why sickle cell anemia was so prevalent in some African populations. How could a "bad" gene-- the mutation that causes the sometimes lethal sickle cell disease -- also be ...

Sickle-cell trait haplotype distribution shows the genetic advantages of this mutation. In the deoxygenated environment of tissue capillary beds, the misshapen RBCs are the cause of all the ...

How do mutations happen, and how do they influence the future of a species? Molecules of sickle-cell hemoglobin stick to one another, forming rigid rods. These rods cause a person's red blood ...

Many individuals with sickle cell anemia undergoing controlled ovarian ... disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell anaemia is also referred to as ...

Jan. 17, 2025 — A new study has found older-looking brains in adults with sickle cell disease, helping to explain the cognitive challenges experienced by such individuals. A brain image from a ...

IMMvention Therapeutix, Inc., a Durham early-stage biotechnology company focused on discovering and developing human ...

Stem cell transplant in young adults and adolescents with severe sickle cell disease may be a feasible option, according to a ...

Children with sickle cell disease, a chronic hemolytic anemia, present with a wide variety ... in the Americas and Europe. The causative mutation is the substitution of valine for glutamic acid ...

New data from a Phase 1b clinical trial testing Fulcrum's pociredir for sickle cell disease are expected by the middle and ...

IMMvention Therapeutix, Inc ., an early-stage biotechnology company focused on discovering and developing human therapeutics, today announced a strategic collaboration and license agreement with Novo ...