结核病，这一曾在历史上肆虐的古老疾病，至今仍在全球范围内对人类健康构成严重威胁。根据世界卫生组织2023年的最新数据，全球新发结核病患者预计达1060万，因结核病而死亡的人数高达130万。幸运的是，绝大多数结核病患者在接受全程规范的药物治疗后都可以被治愈。 一、结核病药物的发展历程 20世纪40年代，链霉素的出现标志着结核病化疗新时代的开启。之后，异烟肼、利福平、吡嗪酰胺及乙胺丁醇等一线抗结核药物 ...

In an exclusive interview with Rashmi Mabiyan Kaur, Dr. Sandeep Nayar, Principal Director and HOD, Chest and Respiratory ...

肺结核耐药检测研究：Xpert MTB/XDR 检测的价值探索 在全球范围内，肺结核（Tuberculosis，TB）这个由结核分枝杆菌引起的传染病，一直是人类健康的大敌。在新冠疫情之前，它甚至比艾滋病夺走了更多人的生命。而多药耐药（Multidrug-resistant，MDR）或利福平耐药 ...

In addition, approximately 9% of MDR TB cases are believed to be extensively drug-resistant (XDR), which entails additional resistance to any fluoroquinolone and to at least one injectable second ...

Antibiotic resistance is one of the most urgent problems facing humanity, but it’s been decades since we last developed a new ...

tuberculosis. Achieving this goal will, however, require overcoming the still perplexing phenomenon of persistence. To effectively treat and control current MDR- and XDR-TB cases, physicians and ...

Conventional TB diagnosis takes 4-6 weeks [8], causing unacceptable delays. Moreover, DOTS requires patients to collect ...

HIV and tuberculosis (TB) will cause the deaths of so many people not only in Africa but also in India and China, that it will change the shape of these societies. HIV and tuberculosis (TB) will ...

But in our analysis, we found that there is a high proportion of pre-XDR in patients who are suspected to be MDR cases.” Whole genome sequencing is considered an advanced form of testing for TB ...