Researchers in the 1960s isolated the first radiation-sensitive mutants in yeast. By the 1970s, researchers had identified a great number of genes that, when mutated, increased the sensitivity of ...

Moreover, the spectrum of mutant phenotypes seen in ohnologues is ... has not contributed any lasting genetic redundancy to the yeast genome. Instead, he suggests that whole-genome duplication ...

But do cells use similar assistance under normal conditions? In late 1987, Horwich and his group stumbled onto a yeast mutant that ultimately demonstrated such assistance was occurring. It became ...

In a previous study, the research team found that mutant yeast cells with defective macronucleophagy (atg39Δ mutants) died rapidly when placed under nitrogen starvation. After careful comparisons ...