A model to predict potential anti-TB drugs is proposed ... required to cross the mycolic acid-rich cell wall, given the good activity of several RNA-active aminoglycosides. The 39 TB drugs ...

This study aimed to calculate the incidence of AKI due to anti-TB drugs and analyze the outcomes and predictors of renal recovery. Methods: From 2006 to 2010, patients on anti-TB treatment were ...

Anti-tuberculosis drug-induced acute kidney injury is not rare in an aging population. It usually develops within two months of treatment and resolves within three months after onset. Although ...

Moreover, BPD-9 was effective against non-replicating (dormant) and intracellular M. tuberculosis, which are two key aspects ...

The Union Health Ministry on Friday also denied a shortage of anti-TB drugs in the country. Noting that media reports claiming scarcity of the drugs are ‘incorrect and misleading,” the ...

Most bacteria have few, if any, P450s but we discovered that the TB bacterium has 20 different types." Even more exciting for the team was the knowledge that existing anti-fungal drugs already target ...

It is a fast, sensitive, scalable and culture-free method that provides a comprehensive anti-TB drug resistance profile, Gueye adds. Managing drug-resistant TB is complex, with more than 20 drugs ...

Now, an international clinical trial has found three new safe and effective drug regimens to treat antibiotic-resistant strains of TB. The results are detailed in a study published January 30 in ...

GSK has expanded a collaboration with BioVersys on a new drug candidate for tuberculosis (TB ... resulting in an increase in the activity of the drug whilst simultaneously overcoming resistance ...