A model to predict potential anti-TB drugs is proposed ... required to cross the mycolic acid-rich cell wall, given the good activity of several RNA-active aminoglycosides. The 39 TB drugs ...

This study aimed to calculate the incidence of AKI due to anti-TB drugs and analyze the outcomes and predictors of renal recovery. Methods: From 2006 to 2010, patients on anti-TB treatment were ...

Moreover, BPD-9 was effective against non-replicating (dormant) and intracellular M. tuberculosis, which are two key aspects ...

The primary goals of this resurgent activity are to shorten and simplify the treatment of active TB, provide safer and more efficacious treatments for drug-resistant TB, simplify treatment of TB ...

Now, an international clinical trial has found three new safe and effective drug regimens to treat antibiotic-resistant strains of TB. The results are detailed in a study published January 30 in ...

[77] The described examples of liposomes as nanocarriers for the delivery of anti-TB drugs using passive and active targeting, as well as some anti-TB drugs efficiently incorporated in liposomes ...

Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including ...

Researchers identified three new all-oral drug regimens that include at least one of two new drugs for treatment of ...

Most bacteria have few, if any, P450s but we discovered that the TB bacterium has 20 different types." Even more exciting for the team was the knowledge that existing anti-fungal drugs already target ...

Drug resistance in M ... afra, has exhibited anti-tuberculosis activity and has long been used in southern Africa to treat ...

GSK has expanded a collaboration with BioVersys on a new drug candidate for tuberculosis (TB ... resulting in an increase in the activity of the drug whilst simultaneously overcoming resistance ...

It is a fast, sensitive, scalable and culture-free method that provides a comprehensive anti-TB drug resistance profile, Gueye adds. Managing drug-resistant TB is complex, with more than 20 drugs ...