生物通29 天
《Nature》揭秘肺癌免疫治疗困境：EGFR 突变与新抗原丢失的纠葛及 ...
为解决 EGFR 突变肺癌治疗中免疫逃逸和靶点选择难题，The Francis Crick Institute 等机构研究人员开展相关研究。发现治疗中克隆驱动新抗原会丢失，明确 WGD 前后突变特点。该研究为优化肺癌治疗策略提供依据，值得一读。 在肺癌的治疗领域，EGFR（表皮生长因子 ...
生物通12 天
新型吡唑基喹啉 - 2 - 酮杂合物：兼具 EGFR 和 BRAFV600E抑制活性的抗癌 ...
为攻克癌症治疗难题，研究人员合成新型喹啉衍生物，发现 4e 可抑制 EGFR 和 BRAF V600E ，有望用于抗癌。 癌症，这个如同恶魔般的存在，一直严重威胁着人类的健康。据国际癌症研究机构（IARC）2022 年全球癌症统计数据显示，当年新增约 2000 万癌症病例，970 万人 ...
新浪网17 天
刚刚，乐普生物回应EGFR ADC情况：主动撤回，今日重新提交NDA
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Healthline23 天
What Is EGFR Mutation in Lung Cancer? Your FAQs Answered
An EGFR gene mutation is one of the biomarkers a doctor often tests for after confirming a diagnosis of non-small cell lung cancer (NSCLC). Biomarkers can help guide treatment. EGFR mutations ...
Medscape10 天
High-Intensity Interval Training Reduces Risk for Kidney Function Decline in Seniors
Long-term high-intensity interval training may reduce the risk for the decline of kidney function in older adults, a study ...
Healio24 天
High-intensity training may reduce rapid eGFR decline risk in older adults
Researched studied participants from the 2012 to 2018 clinical trial who had a median age of 72 years and median eGFR of 95 mL/min/1.73 m 2. The cohort was broken into three groups: 385 patients ...
Healthline1 个月
Overview of EGFR-Positive Lung Cancer
EGFR-positive lung cancer is a type of non-small ... the cancer stage at diagnosis your age and overall health how well the treatments work Your doctor will review all your medical information ...