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全球肾病诊疗新挑战:APOL1基因变异引发的塌陷性肾小球病深度解析
世界卫生组织最新数据显示,慢性肾脏病已位列全球致死疾病增速榜前五。在众多肾小球疾病中,塌陷性肾小球病因其凶险的临床进程引发学界关注:非裔患者群体中高达15%的肾病综合征病例与之相关,且常规激素治疗有效率不足30%。这种伴随大量蛋白尿和肾功能急剧恶化的疾病,正成为现代肾脏病学亟待攻克的诊疗难题。
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