骨折愈合是一个高度协调的过程，涉及炎症、纤维血管形成和矿化。 骨折愈合是一个高度协调的过程，涉及炎症、纤维血管形成和矿化。血管化起着关键作用，因为血液供应不足会严重阻碍愈合。CD47是一种存在于几乎所有人类细胞中的蛋白质，它与组织再生和 ...

CD47-null femoral fractures show reduced bone formation, but increased tissue mineral density. µCT analysis of transverse femoral fracture in WT (n = 9) and CD47-null (n = 11-14) mice at ...

The FDA has placed a partial clinical fold on clinical trials of Gilead Sciences' magrolimab, the centre piece of its $4.9 billion acquisition of Forty Seven in 2020. The regulatory move applies ...

ImmuneOnco Biopharmaceuticals has shown Chinese biotechs are far from immune to the pressures to prioritize pipelines. Eighteen months after listing in Hong Kong, the company has stopped ...

Gilead is dealing with more turbulence in its development of CD47-targeting antibody magrolimab, with a partial clinical hold placed on the drug by the FDA in acute myeloid leukaemia (AML).

ALX Oncology is laying off 30% of its workforce as the biotech seeks to channel its cash into further trials of its CD47 blocker. The drug, called evorpacept, is in a pair of phase 2 trials for ...