为探究 EBV 感染及传染性单核细胞增多症（IM）后能否用血清学指标预测多发性硬化（MS），研究人员检测相关抗体，发现高抗 EBNA-1 IgG 水平与 MS 风险显著相关，高抗 VCAp18 IgG 水平相关性较弱，这为 MS 诊断提供新方向。 # 爱泼斯坦 - 巴尔病毒与多发性硬化 ...

为明确 EBV 感染与 MM 风险的因果关系及免疫细胞的介导作用，芬兰研究人员开展相关研究。结果显示 EBNA-1 抗体或增 MM 风险，HLA-DR? mDC 起介导作用。该研究为 MM 防治研究提供新方向，值得科研读者一读。 在医学领域，多发性骨髓瘤（Multiple Myeloma，MM）是一种让 ...

Increased EBV antibody levels have previously been reported ... of antibodies against the Epstein–Barr nuclear antigen (EBNA) complex, and the date of symptom onset for patients with MS was ...

MS patients start to have increased titers of EBV EBNA-1 antibodies years before MS onset. EBV seroconversion and rising titers of EBNA-1 predict MS onset. Finally EBNA-1 antibodies correlate with ...

In a recent study published in the journal PLOS Pathogens, researchers investigated humoral and cell-mediated immune responses to Epstein-Barr virus (EBV) in multiple sclerosis (MS) patients, post ...