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25 天
HAT1/HDAC2 调控 ACSL4 乙酰化:鼻咽癌放疗增敏的新曙光
该研究首次阐明了 NPC 中 ACSL4 乙酰化修饰对其表达调控的重要性,明确了 HAT1 和 SIRT3 介导 ACSL4 的 K 383 动态乙酰化,为鼻咽癌的治疗提供了新的潜在靶点和理论依据,有望推动鼻咽癌治疗方法的进一步发展。
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