The inaugural Hippo Pathway Targeted Drug Development ... the mechanistic understanding and potential of the Hippo signaling pathway to enhance the discovery, translation, and clinical development ...

These functions are regulated by the interplay of various signaling pathways. The TGF-β and HIPPO pathways are particularly relevant due to their roles in tumor suppression and liver regulation.

Two seemingly disparate signaling pathways -- one that controls organ size in fruit flies and another important for the growth of embryos -- interact in embryonic mouse hearts to restrict cell ...

The lab reported in the journal Science that a gene pathway called Hippo inhibits cardiac muscle regeneration during development. View the Science Journal article. Our lab is currently working to ...