Shown are MRI scans of a Huntington’s disease (HD) sufferer’s brain (left) and a normal brain (right). In the HD brain, many brain cells have died and fluid (black areas) has filled in those ...

HD is a rare, adult-onset, autosomal dominant, progressive neurodegenerative disease. George Huntington (Figure 1) was the first person to provide a comprehensive description of adult-onset HD in ...

Huntington’s Disease (HD) is a condition that stops parts of the brain working properly over time and is usually fatal. There is no treatment for HD and no cure. “This whole thing around ...

Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials Jan. 17, 2025 — Subtle changes in the brain, detectable through advanced imaging, blood and ...

A woman who is at least the fourth generation of her family to suffer a "cruel" brain disorder, which leaves people trapped in their own bodies, is hoping a drug trial can give hope to future patients ...

This type of "somatic expansion" occurs in only the specific types of brain cells that later die in Huntington's disease. Only once a cell's DNA expansion reaches a threshold number of CAGs ...

Its potential in Huntington's disease emerged thanks to an AI drug screening platform operated by SOM, which is used to identify existing drugs that can be repurposed for use in new indications.