It appears that, in addition to inducing cell death, anthracyclines also inhibit protein phosphatase 1, which triggers exposure of calreticulin. Inhibition of protein phosphatase 1 by other drugs ...
and dephosphorylation (catalyzed by protein phosphatases). Protein kinases mediate most of the signal transduction events in cells by phosphorylation of specific substrates - modifying their activity, ...
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