So, compounds that modulate the epigenetic regulation of gene expression, such as HDAC inhibitors, might have antidepressant actions. Nestler and colleagues used a mouse model of chronic social ...

Imprinting is yet another process involved in eukaryotic gene regulation; this process involves the silencing of one of the two alleles of a gene for a cell's entire life span. Imprinting affects ...

When gene regulation fails, or specific genes are ... or convert genetic information into protein products that carry out actions specified in the DNA code. Scientists have long studied the ...

In addition, the use of tools like lentiMPRA and MPRALegNet will help to better equip researchers to unravel the complexities of gene regulation and to explore the vast, uncharted territories of ...

A research team has identified the core gene expression networks regulated ... the precise mechanism of its action was unclear. SRF is a transcription factor directly controlling the expression ...

Along our journey, we shall reveal basic principles of gene regulation. We aim to exploit the new knowledge to help devise novel treatments of many diseases that stem from misregulated gene ...

A research team at KAIST has identified the core gene expression networks regulated ... the precise mechanism of its action was unclear. SRF is a transcription factor directly controlling the ...

As well as being essential in the precise packaging of DNA into the space of the nucleus, histone proteins are also the site ...

A research team at KAIST has identified the core gene expression networks regulated ... the precise mechanism of its action was unclear. SRF is a transcription factor directly controlling the ...

Human health may be getting a big boost from the bits and bytes of computer science. In particular, artificial intelligence (AI) machine learning models are helping to unravel the mysteries of the ...