其中，使用血管内皮生长因子 165（Vascular Endothelial Growth Factor 165，VEGF 165 ）和血小板衍生生长因子 BB（Platelet-Derived Growth FactorBB，PDGF-BB）等生长因子，可促进细胞增殖和血管生成，改善疾病预后。然而，生长因子本身不稳定，易受多种因素影响而降解。将其封装 ...

The ability of tumours to induce new blood-vessel formation has been a major focus of cancer research over the past few decades, and vascular endothelial growth factor (VEGF) is now known to be ...

As a proof-of-principle, we screened human endothelial cells stimulated with vascular endothelial growth factor (VEGF) and constructed a peptide-based ligand-receptor map of the VEGF family.

PDGF stimulates the proliferation and migration of pericytes, vascular smooth muscle cells and fibroblasts. Newly formed blood vessels become stable without further dependence on VEGF when ...

Sorafenib is an oral tyrosine kinase inhibitor able to inhibit VEGF receptors 1, 2 and 3, PDGF receptors α and β, RET, Flt3, c-KIT and the RAF kinase and MAPK pathways. Over 10,000 patients have ...

The key mechanisms include: Cell proliferation: Growth factors such as platelet-derived growth factor (PDGF) and transforming ... Vascular endothelial growth factor (VEGF) promotes the formation ...