Hippo signalling is a cell signalling pathway that controls organ size. Activation of Hippo results in a series of phosphorylation events that culminate in the phosphorylation and cytoplasmic ...

It has long been understood that the Hippo pathway plays a critical role in the development of a wide range of diseases. Although once seen as an elusive pathway, emerging novel data and research ...

The HIPPO pathway can modulate EMT by regulating YAP/TAZ activity. The interplay between these pathways influences EMT dynamics, impacting liver regeneration and disease progression.

The expansion of the Salvador (SAV)–Warts (WTS)–Hippo (HPO) pathway continues with three recent papers that extend the list of upstream regulators and identify links to Wnt signalling.

The researchers also looked at how PI5P4K activity influenced other components of the hippo pathway and found that reduced ...

The lab reported in the journal Science that a gene pathway called Hippo inhibits cardiac muscle regeneration during development. View the Science Journal article. Our lab is currently working to ...