Some examples of anticodon modifications include: Mutations in tRNA genes or defects in tRNA modifications can lead to various genetic diseases. These alterations can affect the structure and function ...

The crystal structure of pseudouridine synthase I from Escherichia coli, which, for example, modifies positions 38, 39 and/or 40 in tRNA, reveals a dimeric protein that contains two positively ...

The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically 73-90 nucleotides long. The key structural features of tRNA include: The specificity of ...

RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases ... coli tRNA Lys triggered by phage-activation of a latent host-encoded anticodon nuclease ...