“This gene-to-molecule research is crucial for discovery in Alzheimer’s disease. It offers fresh perspectives on how genetic risk factors, such as APOE, influence metabolism and perhaps disease ...

Early onset familial Alzheimer disease (eFAD) is hereditary and marked by Alzheimer disease symptoms that appear at an unusually early age. Symptoms can start in a person's thirties, forties, and ...

Brain age gap (BAG) is a useful metric because it predicts one’s age-adjusted vulnerability to a range of neurological disorders, such as AD, dementia, and stroke. Although brain age may indeed ...

Strapped with an extra APP, people with Down’s syndrome are all but destined to develop Alzheimer’s dementia if they live ...

Do you know a conference you think we should list? Let us know by sending us an email with the details to [email protected].

The National Alzheimer’s Coordinating Center unites the collections of the neuropathology cores at 27 NIA-funded AD Research Centers into a single database. It contains records on 13,000 brains, 3,000 ...

Unknown. Multiple in silico algorithms yielded conflicting results.

Alzheimer’s disease is a long, slow neurodegenerative calamity, and scientists are still hunting for blood biomarkers that ...

Dozens of rodents have been generated that model various aspects of ALS, like motor impairment or degeneration of motor neurons. No model recapitulates the human disease perfectly. By organizing ...

Unknown; predicted pathogenic in silico (CADD>20).

“The astrocyte response to AD neuropathology is complex and nonlinear, both along spatial and temporal axes,” Das told Alzforum. She hopes the dataset, which is freely available online, will be a ...