as well as both preclinical and clinical data with select autophagy modulators. Given that the vast majority of PDAC cases have constitutive activation of KRAS, the effects of the MAPK pathway on ...

TFE3 overexpression attenuates α-Syn toxicity in a mouse model of Parkinson's disease. TFE3 overexpression rescues autophagy defects of dop ...

This recent study highlights the neuroprotective potential of TFE3, a transcription factor that plays a pivotal role in ...

Herpesvirus infection may contribute to Alzheimer’s disease through transposable element activation and neuroinflammation.

This study provides a comprehensive exploration of the role of IL-1β signaling during development of lung injury induced by a combination of underlying inflammation and mechanical ventilation. The ...

Many religious fasts coincide with what would once have been periods of scarcity. In this way, fasting served a purpose for millennia. It could serve a very different purpose now.

Longevity research has propelled the scientific community to concentrate on interventions that do more than simply add years ...

Discover how implementing essential morning habits can improve physical and mental health based on recent research and expert ...

Even for people who aren’t religious, there are health benefits of fasting and trends around fasting have taken over social ...

在抗衰领域，新的研究成果与成分不断涌现，非瑟酮（Fisetin）作为一种天然多酚类物质，正凭借其独特的 多靶点调控细胞稳态 的能力，逐渐崭露头角，成为备受瞩目的“抗衰新星”。