The liver is a multifunctional organ that plays crucial roles in numerous physiological processes, such as production of bile and proteins for blood plasma, regulation of blood levels of amino acids, ...

To deconvolute these complex interactions, a more reductionist approach involving microbial metabolites has been suggested. Bile acids have emerged as a key class of microbiota-associated metabolites ...

A potential remedy for this could be the implementation of an ox bile supplement. This natural compound aids the body in breaking down fats and absorbing vitamins soluble in fat. When choosing the ...

But a consistently pale or light poop color may be a sign of a serious medical condition like hepatitis, gallstones, and other liver or biliary (bile duct or gall bladder) diseases. This article ...

Gallstone disease is the most common disorder affecting the biliary system, the body's system of transporting bile. Gallstones are solid, pebble-like masses that form in the gallbladder or the biliary ...

Liver needle biopsy of the patient showed severe cholestasis with bile casts in the canaliculi (Fig. 1). There was mild proliferation of bile ductules, which was accompanied by polymorphonuclear ...

Objective There are altered mucosal functions in irritable bowel syndrome with diarrhoea (IBS-D); ~30% of patients with IBS-D have abnormal bile acid (BA) metabolism (ABAM) and diarrhoea (summarised ...

In another example of the effect of modifier genes, Schiefermeier et al [45] tried to delineate why some patients have later-onset neurologic as well as hepatic symptoms by examining the potential ...

Deleting laminin α4 impairs the connections between megakaryocytes and sinusoids. Megakaryocytes act actively in forming and maintaining this ECM cage, relying on their integrins β1 and β3. Deleting ...