Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

In 1958, Francis Crick's sequence hypothesis finally provided an answer to the question: what is a gene? Why is this definition now considered overly simplistic? Roberts and Sharp also noted that ...

Gene silencing is a negative feedback mechanism that regulates gene expression to define cell fate and also regulates metabolism and gene expression throughout the life of an organism. In plants, gene ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

Recent studies have demonstrated their involvement in regulating gene expression and various biological processes ... in myogenesis of farm animals Skeletal muscle is the main component of animal ...

The team discovered that IPMK binds directly to SRF, altering the three-dimensional structure of the SRF protein. This interaction facilitates the transcriptional activity of various genes through ...

The company, which secured $200 million from investors in a private funding deal last week, learned Tuesday of a serious side effect experienced by one participant on a high dose of its Rett therapy.

In this study, we developed the first single-nucleus multiomics map of chromatin accessibility and gene expression during murine PGC development in both XX and XY embryos. Profiling of cell-type ...

Eye color is a complex genetic trait determined by pairings of genes passed on from each parent. Scientists once believed eye color was determined by a single gene, but advances in genetic research ...

Organisms are made up of cells. Most organisms are multicellular and have cells that are specialised to do a particular job. Microscopes are needed to study cells in detail. In this video, Greg ...

Types 1 and 2 diabetes appear to be caused by an interplay of genetic, environmental, and lifestyle factors. Over the years, researchers have found an array of specific genes that are linked to ...