Researchers have identified a molecular mechanism driving the structural abnormalities leading to lissencephaly that have ...

Lissencephaly is a spectrum of rare, genetic disorders in which the brain fails to develop its hallmark folds. The disorders ...

Gut-Brain Connection. People who have CD83+ microglia in their brains also have HCMV (top left) and IgG4 (top right) in their ...

Yale researchers identified an underactive mTOR pathway as a cause of lissencephaly and reversed brain malformations in patient-derived organoids using a drug. This breakthrough may offer a treatment ...

Lab-grown minibrains, remarkable brain scans and psychedelic trips — take a look back at some of Live Science's most ...

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...

Jan. 11, 2024 — Scientists have produced an organoid model of the human conjunctiva. These organoids mimic the function of the actual human conjunctiva, a tissue involved in tear production.