Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, ...

Charcot-Marie-Tooth (CMT) disease, a group of heritable disorders that affect the peripheral nerves, is marked by specific genetic changes. Research by the team of Prof. Ludo Van Den Bosch (VIB-KU ...

The US Food and Drug Administration (FDA) has granted orphan drug designation (ODD) to NMD Pharma’s oral lead development programme, NMD670, designed to treat Charcot-Marie-Tooth disease (CMT).

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and cellular health, whose failure could be the leading ...

French biotech Pharnext has seen the value of its shares collapse after it revealed that its lead drug, a treatment for Charcot-Marie-Tooth (CMT) disease, failed to make the grade in a phase 3 trial.

This discovery opens new possibilities for treating diseases like CMT. “Although MFN2 is a leading causative gene in Charcot-Marie-Tooth, most other genes linked to the disease do not encode ...

In light of those characteristics, Cellatoz is applying NRPCs, in the form of CLZ-2002, to the treatment of Charcot–Marie–Tooth (CMT) type 1A disease and other health conditions caused by ...

including the application to neurodegenerative diseases such as Charcot-Marie-Tooth disease (CMT) 1, 2. The axonal transport of intracellular vesicle and mitochondria is involved in many ...