To date, development of therapies for AD has focused on agents designed to correct or modulate the loss of cholinergic function within the central nervous system. Various approaches have been ...

Besides the presence of the most abundant γ-aminobutyric acid (GABA-ergic) medium spiny neurons (MSNs), the striatum also contains distributed populations of cholinergic interneurons (ChIs), which ...

Investigations into the influence of modulatory pathways have revealed their ability to affect nearly every aspect of brain function. There are four major ...

Discover how your heart's rhythm reveals stress levels, disease risk and fitness status and provides insights about your ...

Purpose: The pharmacology, pharmacokinetics, clinical efficacy, and safety of rasagiline are reviewed. Summary: Rasagiline is a novel, investigational propargylamine that irreversibly and ...

The two branches of the autonomic nervous system are integrated anatomically and functionally with visceral sensory pathways, and are responsible for the homeostatic regulation of gut function. The ...

Acetylcholine is crucial to brain functions like learning and memory ... DMAE may also increase the risk of seizures. Cholinergic medications act on acetylcholine, a neurotransmitter affecting the ...

6, 2025 — Research in fruit flies has identified specific groups of cholinergic brain cells that ... Uncover Key Mechanisms Related to Cognitive Function Nov. 22, 2024 — While it's well ...

Feb. 6, 2025 — Research in fruit flies has identified specific groups of cholinergic brain cells that are involved in alcohol-induced insomnia. This work could ... Positive Emotions Plus Deep ...

The traditional understanding of inflammation focused primarily on its acute manifestations, the classic signs of redness, ...