The gut is a tubular organ responsible for nutrient absorption and harbors our intestinal microbiome. This organ is composed of a multitude of specialized cell types arranged in complex ...

New research in eGastroenterology identifies the unfolded protein response (UPR) as a crucial mechanism in maintaining intestinal homeostasis and its role in inflammatory bowel disease (IBD) and ...

Mucosal glia in human and mouse small intestines widely express Plp1. C) Whole-mount immunostaining of ileum from an adult Plp1-eGFP mouse for GFAP imaged at the level of the villus-(top panels) and ...

The work will be of interest to colleagues studying intestinal biology. C) Whole-mount immunostaining of ileum from an adult Plp1-eGFP mouse for GFAP imaged at the level of the villus-(top panels) and ...

One example is Wnt signaling, which plays a key role in maintaining stem cell homeostasis within the intestinal crypt. Enteric glial cells have been shown to contribute to this regulation (3). However ...

In the crypts of these mice maintained in a barrier facility there was no evidence of colonisation by commensal gut microflora as detected by silver staining.70 These data suggest that Paneth cell ...

Fear of nuclear fallout has led to a novel therapeutic approach that could significantly extend the lives of individuals with ...

Goblet cells in the vicinity of metaplastic patches also expressed both gastric and intestinal antigens. MUC5AC/MUC2 containing goblet cells were most common near the villus tip but were also seen at ...