Run a brief analysis at the single-cell level, let’s use the common Seurat pipeline. set.seed(12345) sc <- CreateSeuratObject(counts = sc.counts, project = proj.name, meta.data = sc.meta) sc ## An ...

Segal Cancer Proteomics Centre, Lady Davis Institute for Medical Research, Jewish General Hospital and McGill University, Montreal, Quebec H3T 1E2, Canada Division of Experimental Medicine, McGill ...

Methods: Chloroquine was tested in combination with different drugs (Panobinostat, KU-57788 and NU-7026) in 8 human-derived cancer cells lines (colorectal: HCT116 and HT29; breast: MDA-MB-231 and ...

Metaphase chromosome preparations made from CUTLL1 cell line were subjected to G banding and karyotype analysis following standard procedures. Two PAC clones RP11-370H5 and CTD-3242B16 ...

The level of genetic conservation in the cell lines was comparable to that observed with patient-derived xenograft (PDX) models. Unlike historically established PDAC cancer cell lines, patient-derived ...

Interestingly, CADM1 function differs in adult T-cell leukemia/lymphoma (ATLL), and NF-κB is thought to be involved in this process. Taken together, CADM1 could be a potential biomarker for early ...

These structural variants are known to play roles in developmental diseases and cancer, but it has been difficult to study them experimentally. Through creative and collaborative thinking, we’ve been ...

Both 'seed' (the cancer cell) and 'soil' (factors in the organ ... to only a few metastases that are detectable in 'end-point' assays. Similarly, large numbers of cancer cells might be detected ...

9 Affiliated Cancer Hospital and Institute of Guangzhou Medical University ... These results may provide an important theoretical basis for organ-specific CRC metastasis. Human microsatellite stable ...

Salmonella typhimurium TA98 and TA100 (Molecular Toxicology Inc.) were routinely checked to confirm genetic features using the procedure described by Maron & Ames (1983). Cell line M12.C3.F6 (murine B ...

But despite its primary role to prevent pregnancy, the contraceptive pill (or 'the Pill') could also help reduce the risk of ovarian cancer, according to new ... Inhibitor Drugs to Treat ...