Background and Objective: Narcotic analgesics such as hydromorphone undergo an extensive first-pass effect resulting in a low systemic bioavailability following oral administration. Alternative ...

IN doses (treatments B and C) of hydromorphone HCl were administered using a single-dose spray pump (Pfeiffer of America, Princeton, NJ, USA). Patients were asked to gently blow their nose ...

Our editors also may be in touch with follow-up questions. Cannabidiol (CBD) may offer numerous health benefits, including pain relief and anxiety relief, without the intoxicatingly psychoactive ...

Toe pain can happen for a few different reasons. It might be from temporary problems, like a broken toe or blisters, or due to long-term conditions like osteoarthritis or gout. Some health issues, ...

The New Zealand dollar is trading at a nearly two-year low, meaning New Zealanders can expect more pain at the petrol pump. Falling to around 55.5 US cents to the NZ dollar, this rate has not been ...

Epigastric pain refers to pain or discomfort below the ribs in your upper abdomen area. Causes range from acute digestive issues like acid reflux to chronic conditions such as esophagitis.

There are risks associated with penis pumps, particularly novelty pumps. You should discontinue use if you experience pain or discomfort. The overuse of the ED ring can also cause nerve injury that ...

Pain in the right shoulder and arm can occur due to injury, wear and tear, and other health conditions. You may experience other symptoms with certain causes. Shoulder pain is very common. Because ...

Jesse Eisenberg directed movies Eisenberg has begun to take on more directing projects. As we mentioned above, A Real Pain is the second movie he has directed, preceded by When You Finishing Saving ...

“A Real Pain,” which earned Kieran Culkin a Golden Globe on Sunday night, is available to rent/purchase on all digital platforms. It will become available to stream for Hulu subscribers on Ja ...