The aim of the first general part is to give the student an understanding of the main components of the eukaryotic transcription apparatus. Topics covered are: promoters, RNA polymerase II, general ...

In eukaryotic cells, RNA polymerase II synthesizes mRNA in three stages ... we monitored transcription of β-actin and Arc mRNA labeled with MS2 and PP7 stem–loop systems, respectively. After ...

The course focuses on current understanding of the structure and function of eukaryotic transcription factors. Topics covered are: promoters, RNA polymerase II, general transcription factors and ...

Polyunsaturated fatty acids (PUFAs) are important nutrients that play important roles in human health. In eukaryotes, PUFAs can be de novo synthesized through two independent biosynthetic pathways: ...

Shah and colleagues take advantage of the presence of maternal and somatic ribosomes in zebrafish and confirm their differential expression during development. The authors convincingly show that ...

During splicing, which occurs after transcription (i.e., the synthesis of RNA from a DNA template), the introns are removed and the exons are joined, or spliced together.

Now researchers from The Rockefeller University have unearthed intriguing genetic evidence: a protein variant found only in humans that may have helped shape the emergence of spoken language.

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Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...