Ferroptosis is a novel regulated cell death pattern discovered when studying the mechanism of erastin-killing RAS mutant tumor cells in 2012. It is an iron-dependent programmed cell death pathway ...

Objective: This study aimed to identify the mechanism of Yiqi Huayu Decoction (YQHY) induced ferroptosis in gastric cancer (GC) by using network pharmacology and experimental validation. Methods: The ...

基因集富集分析（GSEA）结果也显示，这些基因和甘油三酯代谢过程以及脂质结合途径显著相关。研究人员还发现，在 HCC 中，脂肪酸代谢相关基因 ADH1C 和 ACSL5 的表达与 BRD1 呈负相关，而 FASN、SREBF1、FADS2、ACSL4 和 SCD1 则与 BRD1 呈正相关。在 BRD1 下调的 HCC 细胞中 ...