Our integrated analysis indicated the importance of B-cell metabolic regulation via mitochondrial function in SLE pathogenesis ... as new treatment targets and long-term prognostic markers of SLE.

Vector illustration B-cell and T helper cells B-cell and T helper cells. Basic B-cells function: bind an antigen, receive help from a T helper cell, and differentiate into a plasma cell that secretes ...

Human cytokine standards were provided by the kit and a standard curve was prepared ... To summarize, we show that immunological conditions can dictate the effect of MSC on B cell function. MSC induce ...

Researchers say if their results are confirmed through further study they are optimistic the approach could be used to treat chronic infections for the first time.

A new electrical stimulation therapy for spinal muscle atrophy (SMA) has shown promise in reactivating motor neurons and ...

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions ...

Butyrate suppresses both DC activation and migration to local lymph nodes where activated DCs function to stimulate immature/naive CD4+ T cells to polarize to the Th2 lineage. In the B cell ...

Endosomal recycling is a branch of intracellular membrane trafficking that retrieves endocytosed cargo proteins from early and late endosomes to prevent their degradatio ...

Visualizing cells after editing specific genes can help scientists learn new details about the function of those genes ... effects of knocking out genes in human lung and cervical cancer cells ...

B-cell and T helper cells B-cell and T helper cells. Basic B-cells function: bind an antigen, receive help from a T helper cell, and differentiate into a plasma cell that secretes large amounts of ...

New technologies are helping to establish the roles of human DNA polymerases in cellular functions. These technologies include the creation of cells and ... part b). Assaying the replication ...