Discover how the body’s sleep-wake clocks and dopamine-driven rhythm, influence bipolar mood swings, offering novel treatment ...

New research suggests that mood swings in bipolar disorder are regulated by two clocks: the body’s 24-hour circadian rhythm ...

The research team's next step will be to focus on these molecular "gears" and investigate these potential triggers. More ...

Researchers have identified a second dopamine-driven "clock" in the brain that works alongside the biological 24-hour cycle, ...

More information: Pratap S. Markam et al, Mesolimbic dopamine neurons drive infradian rhythms in sleep-wake and heightened activity state, Science Advances (2025). DOI: 10.1126/sciadv.ado9965 ...