def analyze_tfbs(sequence, snp_position): motifs = jaspar.get_motifs() # Mock JASPAR database query affected_tfs = [] for motif in motifs: if snp_position in motif.instances[0].position: ...

HOMER (Jerković et al., 2017) de novo motif analysis was performed for the sequence set utilizing a 10x random shuffling as a background set. De novo motifs were compared to a vertebrate motif library ...

Then, we will split the sequences in a train and a test sets for machine/deep learning model ... that are commonly used for DNA motif analysis. We will trim and cluster the motifs and compare them to ...

Further, we show that our model can prioritize GWAS variants and learn motifs of transcription factor binding sites. We envision that our model can be useful for delineating cell population-specific ...

SAN FRANCISCO--(BUSINESS WIRE)--Motif, a startup founded in 2023 by design software luminaries Amar Hanspal and Brian Mathews, has secured $46 million in seed and Series A funding to develop a ...

SAN FRANCISCO, January 30, 2025--(BUSINESS WIRE)--Motif, a startup founded in 2023 by design software luminaries Amar Hanspal and Brian Mathews, has secured $46 million in seed and Series A ...

This important study reports single-nucleus multiomics-based profiling of transcriptome and chromatin accessibility of mouse XX and XY primordial germ cells (PGCs). The main conclusions of this study, ...

Abstract: Network motifs provide a deep insight into the network functional abilities, and have proven useful in various practical applications. Existing studies reveal that different definitions of ...

“Indigenous descendants of the original artists have recently explained to us that the rock art motifs here do not simply reflect what the artists saw in the real world,” Jamie ...

Libraries were prepared using the 10X Chromium Single Cell ATAC Library & Gel Bead kit (PN-1000110). In brief, cell nuclei were isolated, and nuclear suspension were incubated in a transposition mix ...