They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for encapsulating genetic materials such as messenger RNA (mRNA) ...

Ionizable lipid nanoparticles (LNPs ... approach to identify an LNP formulation that delivers therapeutic mRNA to the placenta and alleviates hypertension in mouse models of pre-eclampsia.

School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P. R. China ...

We used lipid nanoparticles to deliver mRNA and siRNA to human PCa cells to evaluate our technique's ability to both restore the lost PTEN and silence the overexpressed AR. Our strategy could also ...

Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada Michael Smith Laboratories, University of British Columbia, Vancouver, ...

Yang Zhang, PhD, and Jinjun Shi, PhD, both of the Center for Nanomedicine and Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women's Hospital, are co-senior authors of a ...