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Neuron:脊髓“疼痛开关”Gpr37l1蛋白联手GLT-1,星形胶质细胞竟成慢性 ...
在慢性疼痛过程中脊髓背角区(SDH)的星形胶质细胞增生比神经损伤后的小胶质细胞增生更明显。为探究SDH区星形胶质细胞Gpr37l1是否参与疼痛,研究人员首先通过单细胞测序发现Gpr37l1富集表达SDH区星形胶质细胞,免疫荧光实验证实Gpr37l1可 ...
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