Fats and other cellular materials reach the lysosome through three main pathways: endocytosis, phagocytosis, and autophagy. In endocytosis, the cell takes in materials from outside by wrapping ...

Lysosomes are subcellular organelles that are mainly responsible for degradation of proteins internalized by cells by endocytosis and phagocytosis. Upon uptake, proteins and soluble components ...

Feng Wei at the Institute of Biophysics, Chinese Academy of Sciences, has made significant strides in understanding the BORC complex, a key player in lysosome transport and localization.

Cell cycle re-entry of senescent breast cancer cells after CDK4/6 inhibition (CDK4/6i) constitutes a major source of disease ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, ...

The autophagosomes, autolysosomes and lysosomes can be considered as different stages of the cellular recycling process. Therefore, when cells notice they have too much "junk" inside, autophagy ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

In efforts to create a diverse and accessible stem cell resource, ethnically diverse stem cell lines produced by NYSCF will ...

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Methuosis, a non-apoptotic CD phenotype, occurs when cells accumulate too much fluid by macropinocytosis. In contrast to functional pinocytosis, in methuosis, macropinosomes neither recycle nor fuse ...