The concentrations of remdesivir and GS-441524 were measured using LC-MS/MS. Renal and liver function were assessed. Renal fibrosis was evaluated by Masson’s trichrome staining and Western blotting.

The Masson staining procedure allowed for the differentiation of collagen deposition from ... Subsequent experiments were executed to explore whether ARE influenced the fibrosis progression.

Renal tissue pathological changes were observed by HE and Masson staining; TGF-βl and E-Cadherin protein expressions were detected by immunohistochemistry; E-Cadherin protein expression was detected ...

Treatment with nilotinib also inhibited the development of lung fibrosis in Fra-2 tg mice when assessing the accumulation of connective tissue by Masson's trichrome staining (figure 5G,H). To date, ...

These data were further corroborated with histological tissue staining and fibrosis quantitation based on a Modified Ashcroft (MA) score and a digital image analysis of whole slide lung tissue ...

In 2024, the Reina Sofía Museum has significantly enriched its collection by acquiring 470 new works from 227 artists, both Spanish and international, amounting to an investment of nearly €8 million.

Learn about cystic fibrosis, a genetic disorder that affects the lungs, pancreas, and other organs, and how to treat and live with this chronic disease. 12 min read What Is Cystic Fibrosis? Cystic ...

The best carpet stain removers can be a lifesaver. Many of us have been there, and witnessed that moment when time slows down and a glass of red wine tumbles and splashes across your light carpet.

Skin fibrosis is an often-painful condition wherein the skin thickens and hardens, making it difficult to move. And with no effective treatments currently available, patients are left with few avenues ...

In vivo, sGC stimulation inhibited TGFβ-driven dermal fibrosis but did not change p-SMAD2 and 3 levels and TGFβ target gene expression, confirming that non-canonical TGFβ pathways mediate the ...