The biosynthesis of these alkaloids is complex ... single-cell RNA sequencing to map the spatial organization of MIA metabolism within C. roseus leaves. This research has revealed that the ...

Recent research has focused on understanding the biosynthesis of these alkaloids ... indicating potential pathways for generating a wider variety of BIAs through metabolic engineering[4].

To analyze the impact of gene networks on secondary metabolites and to enhance yields, it is essential to fine-tune the activities of relevant intermediate enzymes, ensuring that each reaction aligns ...

Yerba mate, along with tea and coffee, is one of the world's most popular caffeinated beverages. Widely consumed in South ...

Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, P. R. China ...

A new technology is poised to transform the discovery of microbial species and enzymes with specific in situ metabolic functions. The technology, FISH-scRACS-seq (Fluorescence In Situ ...

Conclusion Oxidative stress, especially through purine metabolism pathway, is a major metabolic event during reperfusion and may contribute to the ischaemia reperfusion injury of lung grafts. Data are ...

However, the roles of C. roseus TCPs (CrTCPs) in terpenoid indole alkaloid (TIA) biosynthesis are largely unknown. Methods: Here, a total of 15 CrTCP genes were identified in the newly updated C.

Uniting our strengths in cell biology, molecular biology, physiology, and pathology, producing a genuinely translational approach to medicine. The Division of Digestive Diseases aims to change ...

View Full Profile. Learn about our Editorial Policies. Diet, weight, and metabolism are intricately linked, so studying their relationship is no easy task. People’s eating habits encompass a wide ...

Cellular specialization appears to activate a) the supply of precursors derived from primary metabolic processes; b) specific biosynthetic pathways for converting primary metabolites into particular ...

Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan ...