In an intriguing revelation from recent research, mitochondria have been shown not only to power the cell but also to ...

the imbalance of mitochondrial fission and fusion, dysregulated mitophagy, mitochondrial DNA mutations and perturbations in the mitochondrial unfolded protein response. Early control of mitochondrial ...

Mitochondria continuously fuse and divide, depending on conditions in the cell, and several proteins regulate this fusion and fission. Specifically, Opa1 and mitofusins 1/2 promote fusion, whereas ...

This demonstrated that aging comes with a decrease in mitochondrial fusion and fission proteins, as seen in previous studies. These decreases would be expected to impair the structure and dynamics ...

The balance between mitochondrial biogenesis and mitophagy helps maintain a healthy mitochondrial population. Mitochondria are highly dynamic organelles, constantly undergoing fusion and fission to ...

melanogenesis in melanosomes that interact with mitochondria through MFN2; (D) autophagosome to lysosome fusion, which is supported by MFN2–RAB7 interaction; and (E) possible phospholipid exchange ...

Objective The crypt population in the human intestine is dynamic: crypts can divide to produce two new daughter crypts through a process termed crypt fission, but whether this is balanced by a second ...