The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

Results: Finally, we find that 860 differentially genes and 2429 dynamic chromatin open regions between normal and hydronephrosis ... That both bile secretion and ascorbate and aldarate belong to ...

Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...

However, enzymes that typically interact with it could no longer recognize these aged regions as chromatin and failed to function. Dr. Luis Guerra explains: "This suggests that chromatin ...

However, enzymes that typically interact with it could no longer recognize these aged regions as chromatin and failed to function. Dr Luis Guerra explains: “This suggests that chromatin, which sets ...

Understanding chromatin accessibility is crucial for deciphering gene regulation and transcriptional control. ATAC-seq provides insight into open chromatin regions, but it does not explicitly define ...

Although stem cell exhaustion is widely recognized as a hallmark of aging, our understanding of cell state changes–specifically, the dynamics of the transcriptome and open chromatin landscape ... To ...

However, enzymes that typically interact with it could no longer recognize these aged regions as chromatin and failed to function. Dr. Luis Guerra explains, "This was a huge surprise for us.

However, enzymes that typically interact with chromatin were unable to recognize these aged regions and failed to function properly. This was a huge surprise for us. Experiment after experiment ...

Department of Chemistry, King’s College London, Britannia House, 7 Trinity Street, London SE1 1DB, U.K.

Rett syndrome is a rare genetic disease affecting 1 in 10,000 newborn girls, characterized by sudden regression around 1 year ...

chromatin states based on chromHMM imputed 25 chromatin states from Roadmap Epigenomics (Ernst & Kellis, 2015; Roadmap Epigenomics et al., 2015), # Ernst, J., & Kellis, M. (2015). Large-scale ...