The accumulation of misfolded proteins in the human brain is one of the critical features of many neurodegenerative diseases, including Alzheimer's disease (AD). Assembles of beta-amyloid (Aβ) peptide ...

Rainwater Prizes honor researchers worldwide who are advancing discoveries for diseases caused by tau protein accumulations ...

Despite distinct clinical and pathological features, these two neurodegenerative diseases share critical processes, such as the presence of misfolded and/or aggregated proteins, oxidative stress, and ...

He, Rice, and others are digging into the biology of various proteins that have been relatively understudied outside the context of the neurodegenerative diseases they’re associated with. “Studying ...

All humans have APOE protein in their genetic makeup ... at the Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases and the Pat V. Orme Endowed Chair in Alzheimer's and ...

WEST LAFAYETTE, Ind. — The shared culprit in a slew of diseases — cancers, neurodegenerative diseases, diabetes — is molecules our cells have made incorrectly. Think of them as proteins gone wrong.

Research finds that 40 percent of dementia cases may be preventable—and healthy diets rich in polyphenols, healthy fats, and ...

Researchers at Tel Aviv University, led by Prof. Illana Gozes, examined the effects of different mutations in the ADNP ...

Lewy body diseases (LBDs) are a class of debilitating neurodegenerative disorders linked to the abnormal aggregation of the protein α-synuclein in nerve cells. When misfolded, this protein can produce ...

Neurogeneticists have discovered a novel genetic mutation and associated buildup of toxic proteins in the brain -- a type of buildup distinct from amyloid or tau, proteins that have long been the ...

The sabotage of cellular messaging, triggered by the formation of chronic stress granules in the brain, may be a key factor ...

AI-powered blood test detects Parkinson's disease years before symptoms appear, revolutionizing early diagnosis and treatment strategies.