The results created 50,000 maps with measurements at more than 29,000 locations across the retina, identifying retinal thinning relating to 294 genes that play an important role in disease. AI ...

Retinal neovascularization (from diabetes mellitus, retinopathy of prematurity and age-related macular degeneration) is the most common cause of blindness 1,2. The present treatment, laser ...

Abstract: Early retinal vascular changes in diseases such as diabetic retinopathy often occur at a microscopic level. Accurate evaluation of retinal vascular networks at a micro-level could ...

Aim To develop a deep learning (DL) model that predicts age from fundus images (retinal age) and to investigate the association between retinal age gap (retinal age predicted by DL model minus ...

Martin Friedlander, MD, PhD, of the Scripps Research Institute in La Jolla, California, presented key findings on novel therapeutic approaches for macular telangiectasia type 2 (MacTel) at this year’s ...

The FDA granted fast track designation to phentolamine ophthalmic solution 0.75% to treat significant chronic night driving impairment in patients who have undergone keratorefractive surgery.

The data will be presented virtually at Angiogenesis, Exudation, and Degeneration 2025 on February 8, 2025. 4D-150 is a potential backbone therapy designed to provide multi-year sustained delivery of ...

Recent genome-wide association studies reveal that single-nucleotide polymorphism (SNP) in MIA3 is associated with atherosclerosis-relevant VSMC phenotypes. However, the role of MIA3 in the vascular ...

These maladaptive alterations in the VSMC phenotype ultimately contribute to vascular diseases. In summary, as crucial components of blood vessels, VSMCs are tightly regulated by various SIRTs that ...

Inhibition of VEGF expression is critical to slow down the progression of DR, so VEGF is one of the key targets in studying the early lesions and retinal protection of DR (Jin et al., 2023). HIF-1α is ...