Glucose Transporter 1 Deficiency Syndrome (Glut1DS) is a rare genetic disorder caused by mutations in the SLC2A1 gene, which impairs the transport of glucose across the blood-brain barrier.

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

Each gene tells a cell to make a specific molecule, but this isn't performed by the DNA itself. Instead, the information is relayed to cellular machinery by a molecule called messenger RNA.

These could be signs that you have an inherited intolerance to alcohol — and a mutated gene could be the culprit, according to Cleveland Clinic. This gene mutation hampers the body’s ability ...

Jan. 21, 2025 — Trypanosomes are parasites that cause sleeping sickness, Chagas disease, and various animal diseases. Diagnosis and treatment remain complex and no effective vaccine has been ...

Objective Macrophage activation by monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals mediates an interleukin (IL)-1β-dependent inflammation during gout and pseudo-gout flare, ...

This important work identifies a non-autophagic role for ATG5 in lysosomal repair and the trafficking of the glucose transporter GLUT1 to the cell surface, mediated through the retromer complex. The ...

Centre for Proteomic Research, School of Biological Sciences and Institute for Life Sciences, University of Southampton, Building 85, Southampton SO17 1BJ ,U.K. Centre for Cancer Immunology and ...

New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms. Every biology student ...