Mist1CreERT;R26-Tdtomato;Lgr5DTR-eGFP mice were used to ablate the corpus basal Lgr5+ cell population. Constitutional and conditional Wnt5a knockout mice were used to investigate the role of Wnt5a in ...

M. Kirby Neurobiology Center, Boston Children’s Hospital, Department of Neurology, Harvard Medical School, Boston, United States Research Unit for Blindness Prevention of the Chinese Academy of ...

研究团队首先利用冷冻电镜解析了人源VANGL1和VANGL2蛋白的高分辨率结构。二者均组装成具有D3对称性的六聚体，首先由单体组成紧密结合的三聚体 ...

团队还在子宫内膜基质细胞中发现了WNT5A的上调和非经典WNT信号的异常激活，这可能有助于病变的形成，为治疗干预提供了新的靶点。 最近，单细胞转录组测序被用于分析子宫内膜异位症部位内和部位间的细胞异质性，以及整个月经周期中子宫内膜的动态重塑。

A puzzle for millennia, the movement of blood through the body was solved by an English physician in the 17th century, paving the way for modern medical technologies. Dhun Sethna is a cardiology ...