After pre-mRNA processing, mRNPs would interact with NPCs, perhaps through Mex67 and Mtr2 (TAP and p15). The Yra1-Mex67 interaction may be crucial for this. If additional studies confirm that Yra1 ...

Professor Vlad Pena's group focuses on the structural basis of human pre-mRNA processing under normal, pathological and drug-induced conditions. Imogen is a PhD student in the Division of Structural ...

Insights into protein synthesis processes in prokaryotes and eukaryotes are crucial for advancements in genetics, ...

In total, these results indicate that inhibition or slowing of canonical pre-mRNA processing events shifts the steady-state output of protein-coding genes towards circular RNAs, which likely helps ...

Penn Engineers have made a critical breakthrough that bridges a major healthy equity gap for pregnant people with ...

The Lai lab uses an integrated approach to study selected topics in mRNA processing and modification, including alternative polyadenylation, circularization and RNA methylation. As a core member of ...

A comprehensive study identifies sequence features that predict tissue-specific alternative splicing. In contrast to transcription and translation, in which the flow of information from DNA to pre ...

(Image: ttsz/iStock via Getty Images Plus) The Role of mRNA in Gene Expression Messenger RNA is an essential component of the gene expression process, which involves the conversion of genetic ...