Ezrin, a major membrane-actin linker that assembles and coordinates macromolecular signaling complexes at membranes, has emerged recently as an important regulator of lysosomal function. Here, we ...

The pleura (plural: pleurae) is a two-layered membrane that covers the lung. Between the layers is a small amount of lubricating fluid, known as pleural fluid, which helps cushion the lung and reduce ...

Feng Wei at the Institute of Biophysics, Chinese Academy of Sciences, has made significant strides in understanding the BORC complex, a key player in lysosome transport and localization.

Cholesterol is a crucial component of cellular membranes, enabling hormone production ... in organelles with varying acidity, such as lysosomes and lipid droplets. Compared to traditional ...

Lysosomal exocytosis occurs when the lysosomes fuse with the plasma membrane of a cell to expose and release their contents outside of the cell. Essentially, lysosomes and lysosomal exocytosis act ...

GDAP1 and MFN2: the OMM proteins GDAP1 and MFN2 are involved in MLCS by interacting with LAMP1. TM4SF5: TM4SF5 translocates to the lysosomal membrane in response to extracellular glucose availability ...

Key Laboratory of New Membrane Materials, Ministry of Industry and Information Technology, School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing ...

This important work identifies a non-autophagic role for ATG5 in lysosomal repair and the trafficking of the glucose transporter GLUT1 to the cell surface, mediated through the retromer complex. The ...

Background: The lysosome plays a vitally crucial role in tumor development and is a major participant ... The electrodepositionally separated proteins were then transferred onto a polyvinylidene ...

Lysosomal exocytosis occurs when the lysosomes fuse with the plasma membrane of a cell to expose and release their contents outside of the cell. Essentially, lysosomes and lysosomal exocytosis act ...