Topline data readouts from multiple Phase 2 studies expected throughout 2025VTX2735 in patients with recurrent pericarditis in H2VTX3232 in ...

The ‘NLRP3 inflammasome’ is like a control switch. In Alzheimer’s disease, its activation triggers an inflammatory response ...

Scientists from DZNE, University Hospital Bonn, and the University of Bonn have found new evidence that reducing brain inflammation could help treat Alzheimer’s disease. Their research, published in ...

为解决放射性皮肤损伤（RISI）中衰老细胞清除障碍问题，陆军军医大学研究人员研究巨噬细胞中 NLRP3 在 RISI 中的作用，发现其可促进衰老细胞清除，Nr-CWS 有治疗潜力。该研究为 RISI 治疗提供新思路，值得一读。 在癌症治疗的战场上，放疗是一把双刃剑。

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. No ...

The inflammasome is a multiprotein intracellular complex that detects pathogenic microorganisms and sterile stressors, and that activates the highly pro-inflammatory cytokines interleukin-1b (IL ...

Specifically, we pharmacologically manipulated a molecular complex called the NLRP3 inflammasome. It is found in microglia, which are the immune cells of the brain,” says Dr. Róisín McManus ...

Specifically, we pharmacologically manipulated a molecular complex called the NLRP3 inflammasome. It is found in microglia, which are the immune cells of the brain." Dr. Róisín McManus ...

The “NLRP3 inflammasome” is like a control switch ... NLRP3 not only reduces neuroinflammation, but also helps microglia clear the harmful amyloid-beta deposits, a process called phagocytosis.